Color Variation in Tablet Coating

 This problem is most often caused by an error in the parameter or setting of the machine reasons for this problem.

 

1. Inappropriate pan speed, too high or too low.

Solution: Work at a pan speed appropriate to the shape ot tablets.

 

2. The solution was not prepared and dissolved properly.

Solution: Prepare the solution properly .

 

3. The number of guns is not suitable compared to the size of the patch.. 

Solution: Increase the number of guns.

 

4. The percentage of solid content in the solution is very high, which leads to poor color performance and poor distribution. 

Solution: Reduce the percentage of solid content in the solution.

 

5. Insufficient solution for operation. 

Solution: Increase the amount of solution.

 

6.  A large variation in spray rates between each gun and the other.

Solution: Test the guns before starting operation. 

 

7. The very high temperature that leads to the solution drying before it reaches the tablets. 

Solution: Reduce the temperature to reach the solution appropriately.

 

8. Poor pattern air setting 

Solution: do a pattern test before the process .

 

9. The distance between the guns and tablets is too far . 

Solution: Reduce the distance between the guns and the tablets.

 

10. Poor spray angle. 

Solution: Adjust the spray angle.

 

 11. the movement of the tablets in the drum is not appropriate and is the result of a bad design of the baffles or a patch size that is too large for the machine’s capacity.

Solution: Change the type of baffles and modify the batch size.

 

12. When weight gain is very little.

The solution: work on a higher weight gain.

 

13. High suction rate, which leads to the loss of a large amount of spray.

Solution: Adjust the pressure and check the filters.

 

14. High spray rate during coating process and loose more solution in drying.

Solution : decrease the spray rate.

 

Read also: 

 

Resource Person: Shady Mansour

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