Types of Disinfectant in Pharmaceutical Industry

High-Level Disinfectant

High-level disinfectant is a type of cleaning agent that’s proven to be effective at killing certain pathogens, viruses, bacteria, fungi, spores, and other contaminants. It’s designed to eliminate a wide range of microorganisms that can cause health-related issues or contribute to an outbreak in the community. High-level disinfectants are considered the strongest form of disinfection available and, therefore, are often used in healthcare facilities or other settings where the risk of infection is higher than average.

Example of a high-level disinfectant

Greater than or equal to 6% Hydrogen Peroxide
0.55% Ortho-phthalaldehyde (OPA)
1:10 Chlorine Bleach Solution

Intermediate-Level Disinfectant

Intermediate-level disinfectant refers to the agent that kills a wider range of pathogens than a low-level disinfectant but does not kill bacterial spores.

Intermediate level disinfection should be considered for environmental surfaces that are visibly contaminated with blood

Example of a intermediate-level disinfectant

70% Isopropyl or Ethyl Alcohol
1:50 Chlorine Bleach Solution
0.5% Hydrogen Peroxide

Low-Level Disinfectant

low-level disinfectants are considered to be the mildest form of disinfectant available. However, they’re still formulated to kill several different types of vegetative bacteria, some kinds of fungi, and a few viruses. They’re generally safe to use on any non-critical item that comes in contact with skin but doesn’t require more intensive sterilization. They’re typically composed of quaternary ammonium compounds but can also include hydrogen peroxide and sodium hypochlorite. Most often, low-level disinfectants are used in settings that don’t require more intensive cleaning.

Example of a low-level disinfectant