BCS Classification

Biopharmaceutics Classification System (BCS)

Biopharmaceutics Classification System (BCS)

The BCS categorizes drug substances into four BCS classes as follows:   What is High Solubility? The highest dose strength of the drug can be dissolved in ≤ 250 mL of aqueous media at a pH from 1 to 6.8 (including pH = pKa, pH = pKa + 1 and pH = pKa-1) and a temperature of 37 °C ± 1 °C.     What is High Permeability? The fraction…