Mottling Uneven distribution of color or pigmentation on the tablet surface. Causes of Mottling: Remedies for Mottling: Flashing It presents as a thin, unwanted edge around the perimeter of a tablet. Causes of Flashing: Remedies for Flashing: Chipping Breakage of tablet edges, resulting in small chips or fragments….
1. Capping Partial or complete separation of a tablet’s crown or upper portion from the main body. Causes of Capping: Remedies for Capping: 2. Lamination Tablets split into layers or laminates. Causes of Lamination: Remedies for Lamination: 3. Sticking It happens when the tablet material adheres to the punches and dies instead…
Pharmaceutical tablets must meet their physical specifications and quality standards for ensuring safety and efficacy. These include weight variation, content uniformity, hardness, thickness, friability, disintegration, and dissolution. These factors must be controlled during production (in-process controls) and verified after the production of each batch to ensure that established product quality standards are met. Weight…
Tablet is the most common and convenient dosage form. Itcontains active ingredient(s) and excipients. The various types of tablets aredescribed as follows: Compressed Tablets In addition to the API(s), compressed tablets usually contain a number of pharmaceutical excipients, including diluents or fillers, binders or adhesives, disintegrants or disintegrating agents, anti-adherents, glidants, and lubricants to prepare…
