Tablet Compression Cycle
There are three stages involved in this cycle:
- Filling stage
- Compaction stage (Pre-Compression & Main Compression)
- Ejection stage
1) Filling stage
At the filling stage you have to adjust the lower punch to die for which fill depth setting needs to be done in such a way that required powder only gets filled to maintain the tablet weight. So this part becomes very important as far as tablet weight is concerned.
2) Compaction stage
A. Pre-compression:
At this stage with a slight compaction of defined loads binds these granules and forms a tablet without gaining required hardness ,weight and thickness.
Yes, but this stage helps tablets to achieve these parameters in the main compression stage.
without this stage tablet may not achieve required hardness or fail in friability test or may have erosion, sticking or picking issues and many more other issues unless your granules are free flow in nature,non sticky or moisture sensitive.
B. Main Compression Stage
The final compression to shape a tablet occurs at this stage. Tablets get compressed at defined load to achieve the required weight, hardness and thickness. These loads are generated by rollers on both upper and lower punches which vary from 2 Tons to 10 Tons.
3) Ejection Stage
After forming the tablet shape ,it is equally important to eject them without causing any damage .For that ejection blade setting becomes very important, mostly in case of shape (caplet, oval, animal and any other special shape) tablets setting should be in such a way that the length of the tablet should come in contact with the ejection blade to avoid jumping off the tablet.
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