Tablet compression is a complex process influenced by multiple critical factors, including: Material Properties: Particle size, shape, flowability, and moisture content of the powder blend Compression Force: Magnitude and duration of pressure applied by the punches Lubrication: Type and amount of lubricant used to reduce friction and prevent sticking Die & Tooling: Surface finish, clearance,…
In tableting the compaction force is a crucial parameter that is a major driver for the final product’s properties. But its influence varies across different characteristics: 1. Weight and Weight Uniformity: In general, the weight of tablets remains unchanged by compaction force, ensuring dosage consistency but on rotary tablet presses the weight uniformity sometimes…
There are three stages involved in this cycle: 1) Filling stage At the filling stage you have to adjust the lower punch to die for which fill depth setting needs to be done in such a way that required powder only gets filled to maintain the tablet weight. So this part becomes very important…
