Materials are Used in Pharmaceutical Blister Packs
Aluminum Foil:
Aluminum foil offers the highest barrier overall, against both moisture and oxygen, completely blocking light and gases. Aluminum foil used for highly sensitive drugs due to its exceptional impermeability.
Ethylene Vinyl Alcohol (EVOH):
oxygen barrier properties, particularly in dry conditions,but is moisture sensitive and often used in multilayer films with hydrophobic outer layers to protect it from humidity.
PVDC (Polyvinylidene Chloride):
Offers strong moisture and gas barrier properties, commonly applied as a coating on PVC films in blister packs to significantly improve protection against moisture and oxygen.
Aclar (Polychlorotrifluoroethylene, PCTFE):
Provides excellent moisture barrier capabilities combined with transparency, making it suitable for pharmaceuticals requiring moisture protection.
Multilayer Films:
Combinations of materials such as EVOH with polyethylene or PET enhance barrier performance by balancing oxygen protection and moisture resistance.
Advanced technologies including nanotechnology and microfibrillated cellulose composites have further improved barrier materials by sealing micro-pores and maintaining barrier integrity under varying humidity.
Read also: Advanced Materials And Technologies in Pharmaceutical Packaging
Resource Person: Marwa Abdallah
