Bubble point integrity testing is a method used to evaluate the largest pore size in a filter or membrane. This test is based on the principle that when a liquid is forced through a filter, it will flow through the larger pores first. As the pressure increases, the liquid will eventually penetrate the smaller pores,…
Terminal sterilization refers to the process of sterilizing a product or substance at its final stage of packaging, usually using heat or radiation. In the pharmaceutical industry, there are several methods of terminal sterilization employed, each with its own advantages and disadvantages. Here are some commonly used methods: 1. Autoclaving – Advantage: Autoclaves…
The frequency of Sterilization In Place (SIP) in the pharmaceutical industry can vary based on the type of sterilization method being used. Here are some common types of sterilization and their associated frequencies: 1. Steam Sterilization: This is one of the most widely used methods in the pharmaceutical industry. The frequency of SIP for…
