Effect of Granule Particle Size on Dissolution of BCS Class 2 & 4 Drugs
Granule particle size plays a pivotal role in drug dissolution, especially for BCS Class 2 (low solubility, high permeability) and BCS Class 4 (low solubility, low permeability) drugs. Here’s how: Key Factors to Consider: 1. Surface Area vs. Dissolution Rate: 2. Porosity and Wetting: 3. Granule Size Distribution: Why It Matters for BCS Class 2…
